The Gioconda Smile is a psychological story of deception, desire, and murder, first published as part of Mortal Coils. Aldous Huxley explores hidden motives, strained relationships, and emotional manipulation through the life of a man trapped between his dying wife and his obsessive lover.

The story later inspired a stage adaptation and is known for its dark irony, sharp social observation, and exploration of guilt, appearances, and destructive passion.